CAS Number:
1642-54-2
Category:
Anthelmintic
Regulatory Status:
WHO Approved
regulatory_status
CEP/EDMF:
-
Innovator Brand:
Hetrazan
Therapeutic Area:
Anti-Parasitic
USDMF:
#026954
Others:
WHO approved
Mechanism of Action
Diethyl Carbamazine Citrate works by killing both the adult worms and their larvae in the blood. It is thought to act as an agonist at the arachidonic acid cascade, causing enhanced production of leukotrienes. This results in inflammation and eventual death of the parasites.
Uses
Diethyl Carbamazine Citrate is used to treat certain types of worm infections, specifically filariasis including lymphatic filariasis and river blindness (onchocerciasis).